Definition—davidbdale

Political Paralysis

How many children will we need to paralyze to eradicate polio forever? Increasingly, as we approach the ultimate goal of eliminating a crippling disease once and for all from the planet, we must confront this grim calculation. Until the turn of this new century, the naturally-occurring—or wild—polio virus was the primary way for the disease to reach its human hosts, causing illness, debilitation, partial or total paralysis, even death, usually of children, almost always in remote villages ill-served by health agencies. But since the certified eradication of Type 2 polio, and the near elimination of Types 1 and 3, the primary way polio infects its hosts is, I hesitate to say it, through our own inoculation campaigns.

The twentieth-century eradication of smallpox must have emboldened us to imagine that ridding the world of polio would be a matter of course. After all, according to Donald Henderson’s “The Eradication of Smallpox—An Overview,” smallpox had killed 300 million people in the 20th century alone, “more than twice the death toll of all the military wars of that century.” Compared to that massive, almost always deadly scourge, polio, which paralyzed children but killed few and was almost never contracted by adults, must have seemed like an easy target for elimination.

But polio turned out to be a different case altogether: less deadly but sneakier, more resistant to both serums and human effort.

First of all, smallpox is easy to spot. As Henderson again notes, this time in “Countering the Posteradication Threat of Smallpox and Polio,” smallpox is readily visible. Sufferers are covered over most of their body with distinctive purulent poxes. Unlike polio, which can hide in the body for years while its bearers infect others, smallpox advertises its presence and makes intervention much more likely. Imagine trying to rid the world of a disease that has more than 200 asymptomatic carriers for every paralyzed patient.

Second, polio vaccines need to be administered several times, on a schedule, to be effective. Whereas for smallpox, again according to Henderson, a single dose of vaccine immunizes nearly 100% effectively, polio requires at least three doses of Oral Polio Vaccine (OPV). And fewer than six doses might not achieve a 90% protection against the predominant strains: types I and III. In stable communities with the enthusiastic support of the local population and health agencies, inoculating every child under five with six doses of anything on a scheduled basis would be seemingly indomitable. But, add to that the social and environmental instability of the areas where polio is endemic (Afghanistan, Pakistan, North and West India, and Nigeria), where flood, famine, and warfare shred the social fabric, and the job seems beyond human capability.

Finally, the vaccines themselves can infect patients with the virus. This is the most insidious and infuriating frustration of the fight against polio. What at the start of the campaign was an almost negligible nuisance factor (if lifelong paralysis can be discounted) of 1 case per 3 million doses of vaccine, has become—tragically and ironically—a much more significant drawback of the seemingly endless effort to finally eradicate polio.

Aylward and Tangermann relate the confident enthusiasm of the polio eradication campaign of the early 1980s, fueled by a strong start and rapid success.

By the year 2000, the incidence of polio globally had decreased by 99%. . . . By 2002 . . . the Americas, Western Pacific and European Regions had been certified polio-free. By 2005, . . .  wild poliovirus (WPV) had been interrupted in all but 4 ‘endemic’ countries: India, Nigeria, Pakistan and Afghanistan, where eradication efforts effectively stalled.

Momentum is everything in eradication campaigns. The effort is global and requires the cooperation of entire continents. Adversaries in everything else need to put aside their differences—sometimes even calling cease-fires on battlefields—to cooperate in delivering preventive measures to diverse populations regardless of their race or nationality. What had occurred so naturally in the eradication of smallpox needed to occur again if polio was to be eliminated. Henderson described it this way:

The scope of the smallpox program was unprecedented. It required the cooperation of all countries throughout the world and the active participation of more than 50. It was a universal effort unlike any that had ever been undertaken. Most countries eventually proved to be readily responsive but strong persuasion was necessary for some. National antipathies were generally set aside.

In both efforts, the vast majority of the population in endemic countries were inoculated in the early years. And in both cases complications of population movement, natural disasters, maddening bureaucracy, and dislocations of regional conflicts and civil wars frustrated the mass inoculations. But the polio campaign has not yet overcome the elemental differences of the two diseases that make the ultimate elimination of polio so much less likely.

Like the smallpox campaign, the effort to eradicate polio scored impressive early successes. According to Aylward and Tangermann, “By the year 2000, the incidence of polio globally had decreased by 99% compared with the estimated number of cases in 1988 . . . and the last case of polio due to wild poliovirus type 2 transmission anywhere in the world was recorded in Uttar Pradesh, India in 1999.” And then the effort stalled.

Polio is not smallpox: obvious, defenseless, stable. It’s nefarious, invisible until it strikes, and mutable. The 1% of cases that persisted after 2005 began to mutate. The world had failed to wipe out the last of the last viruses. Some children had only mucosal immunity while the virus thrived in their intestines. The carriers looked healthy but passed the virus to others undetected, especially in the toughest places, the remote villages and refugee camps where sanitation was crude at best and healthcare nonexistent.

And while the agencies assigned to eradication tried to counter the mutations with customized variations of the Oral Polio Vaccine to meet local conditions, mounting resistance to an intrusive, expensive, and seemingly endless global eradication effort weakened the support needed to force the effort past the last 1%. According to Taylor, Cutts, and Taylor, in the American Journal of Public Health, “Negative effects were greatest in poor countries with many other diseases of public health importance.” It’s not hard to imagine the reluctance of villagers in India, for example, whose children routinely die of diarrhea, objecting to the massive effort to eliminate polio, which many have never seen, and which does not kill.

There was blessed, magnificent, altogether positive enthusiasm at the UN, at the WHO, at Rotary International, in the 1980s, that the world could once again achieve with polio the triumph of man over disease that had been accomplished against smallpox. But similar efforts achieve similar results only when conditions are similar, and smallpox and polio are too different for the same formulas to work.

References

Aylward, B., & Tangermann, R. (2012, April 06). The global polio eradication initiative: Lessons learned and prospects for success. Retrieved February 12, 2018, from https://www.sciencedirect.com/science/article/pii/S0264410X11015994?via%3Dihub

Henderson, D. A. (2002, January 01). Countering the Posteradication Threat of Smallpox and Polio | Clinical Infectious Diseases | Oxford Academic. Retrieved February 12, 2018, from https://academic.oup.com/cid/article/34/1/79/312029


Questions for You

Answer with a Reply below.

  1. How is this a Definition Essay? It doesn’t define polio, smallpox, or eradication.
  2. What is the clearest and briefest statement of the thesis of this argument?
  3. What differences between polio and smallpox make it less likely that polio can be eradicated?

38 Responses to Definition—davidbdale

  1. stripedsweater21's avatar stripedsweater21 says:

    -It is a definition essay because it reveals the severity of the diseases. It doesn’t give a dictionary definition of polio, smallpox or eradication, but it gives a clear indication of what they are and how important/severe they are.
    -The clearest and briefest statement of the thesis is that “smallpox and polio are too different for the same formula to work”.
    -Polio is not detectable until the infection has taken place- as the text says, “Polio is mutable until it strikes”. This makes it extremely difficult to know who has polio, therefore we cannot give someone treatment if we do not know if they have polio.

  2. harp03's avatar harp03 says:

    1. It is considered a definition essay because it, “technically”, defines polio and smallpox by explaining how they effect people, the death rates of them, and simple compare/contrast analysis. The essay also explains eradication by using statistics and describing how polio had almost been completely gone, but that it had broken out again and had never achieved 10 years of no cases (the definition of eradication). This enables the reader to understand what the terms mean without using a dictionary definition.
    2. The main argument of the thesis is that polio and smallpox have received different support for being eradicated, and that they are different diseases. Therefore, polio and smallpox require different strategies when attempting to eradicate them. (smallpox has already been eradicated, of course)
    3. Polio is invisible until it strikes, as well as mutable, more resistant to serums, and it is not as deadly as smallpox. Meanwhile, symptoms of smallpox are very visible, and it is a very deadly disease. For these reasons, the diseases are very different, and due to their differences the momentum and effort to eradicate polio is less involved than it was for smallpox.

  3. sixers103's avatar sixers103 says:

    1. It is a definition essay because throughout the essay it defines what the disease is capable of doing and who it will greatly affect.
    2. The clearest and briefest statement is that polio and smallpox are two completely different diseases that won’t allow the for the same formula to work.
    3. Smallpox can be visible to the human eye and polio cannot which means polio is much harder to be diagnosed without being tested for.

  4. ChefRat's avatar ChefRat says:
    1. How is this a Definition Essay? It doesn’t define polio, smallpox, or eradication.
    • It’s a definition essay because while it doesn’t directly state what all these 3 things are, there are clear connotations and comparisons to one another to help the reader perceive what the topic is.
    1. What is the clearest and briefest statement of the thesis of this argument?
    • “Smallpox and polio are too different for the same formula to work.”
    1. What differences between polio and smallpox make it less likely that polio can be eradicated?
    • The difference is Polio is much more nefarious, it’ll hit you when least expect it and fast. With the ability of mutation there will be adaptations necessary.
  5. lil.sapph's avatar lil.sapph says:
    • It is a definition essay as while it may not tell the reader EXACTLY what it is, it tells the reader everything it does and who it affects , and compares it to smallpox showing how its not the same disease at all.
    • The clearest statement of this argument would be “Polio is not smallpox: obvious, defenseless, stable. It’s nefarious, invisible until it strikes, and mutable.”
    • This statement is also the reasons why it is less likely for polio to be eradicated. By the time polio is found, its already rapidly progressing so it is very hard to cure, and when a cure is found, it mutates leaving the cure ineffective
  6. student1512's avatar student1512 says:

    I believe this example did help my understanding. Here are my class notes where I’m figuring it out:

    -thought we could have eradicated polio, because we did it with smallpox. Is this a categorical argument yet?

    -Under what conditions?

    -We think they are similar enough that the analogy will hold.

    -We think polio is similar to smallpox so that the same conditions will be met. They’re under the same category.

    -Looking to accomplish, decide whether the analogy between smallpox and polio to argue by analogy, they belong to the same category, conditions are similar enough. Under this question they are analogous.

    -What are the conditions?

    -smallpox eradication, polio not: different characteristics. Define those and see if they fit under the same category.

    • student1512's avatar student1512 says:
      1. How is this a Definition Essay? It doesn’t define polio, smallpox, or eradication.

      This is a definition essay as it compares both between a category and defines rather what they are not.

      1. What is the clearest and briefest statement of the thesis of this argument?

      “smallpox and polio are too different for the same formula to work”.

      1. What differences between polio and smallpox make it less likely that polio can be eradicated?

      To quote the essay, “Polio is not smallpox: obvious, defenseless, stable. It’s nefarious, invisible until it strikes, and mutable. The 1% of cases that persisted after 2005 began to mutate.” Its because of these type of mutation and inability to detect that this disease is less likely to be eradicated. If it ever even can.

  7. iloveme5's avatar iloveme5 says:
    1. It is a definition essay because although it doesn’t define the disease it explains what it causes, what it does, and its effects it has.
    2. The clearest and briefest statement of this essay is that they are two different diseases and its eradication differs from each other. “Polio is not smallpox: obvious, defenseless, stable.”
    3. The differences between polio and smallpox make it less likely that polio can be eradicated are that it has different characteristics one is not noticeable until it’s too late or unless tested for it. One can be eradicated forever the other can’t. Smallpox is visible and is not as deadly.
  8. Robofrog's avatar Robofrog says:
    1. By comparing two different diseases.
    2. The clearest statement is “smallpox and polio are too different for the same formulas to work.”
    3. Cost of vaccination, visibility of the effect of the diseases, lethality of the diseases
  9. Mongoose449's avatar Mongoose! says:
    1. How is this a Definition Essay? It doesn’t define polio, smallpox, or eradication.
      • It defines how polio does not relate to smallpox, and how you can’t use one example of an eradicated disease to perceive and explanation how to eradicate another.
    2. What is the clearest and briefest statement of the thesis of this argument?
      • “Smallpox and polio are too different for the same formula to work”.
    3. What differences between polio and smallpox make it less likely that polio can be eradicated?
      • Polio is an insidious killer, it waits inert for months or even years at a time, it can be transmitted without symptoms and can spread for years before a case is detected. Smallpox is easily identifiable; poxes show on the skin and is both able to be discovered and treated. You cannot easily eradicate a disease that cannot be found.
  10. loverofcatsandmatcha's avatar loverofcatsandmatcha says:
    1. By comparing smallpox and polio, and determining that they are NOT similar, it does provide a roundabout way of a definition.
    2. The cleareset statement is: “Polio is not smallpox: obvious, defenseless, stable. It’s nefarious, invisible until it strikes, and mutable.” because it clearly defines what it is not, so we can narrow down what it is.
    3. Polio is harder to eradicate because it lays dormant for significantly longer than smallpox. People could have it and have no idea, whereas smallpox is apparent immediately, and can be quarantined.
  11. SkibidySigma's avatar SkibidySigma says:
    1. This essay is a Definition Essay because it provides a broader understanding of the concept of “eradication” by discussing the challenges involved in the effort to eliminate polio.
    2. The thesis of this essay is: Unlike smallpox, polio is harder to eradicate due to its ability to remain invisible in carriers, the complexity of its vaccination requirements, and religious beliefs.
    3. Polio is harder to eradicate than smallpox due to several factors. Unlike smallpox, polio can remain invisible, making it harder to detect. Polio requires multiple vaccine doses, whereas smallpox needs only one. Moreover, instability in endemic regions hinders consistent vaccination. These factors make polio eradication significantly more challenging.
  12. student12121's avatar student12121 says:
    1. How is this a Definition Essay? It doesn’t define polio, smallpox, or eradication.

    It defines an eradicable disease. It may not define all of the parts but an eradicable disease on the world stage is defined and the author puts smallpox but not polio in that category.

    1. What is the clearest and briefest statement of the thesis of this argument?

    Polio is not an eradicable disease.

    1. What differences between polio and smallpox make it less likely that polio can be eradicated?

    Polio is not visible. The inoculation carries risk. Polio is less big on the world stage, many people don’t think about polio for months at a time. The problem is not on the forefront of many peoples minds.

  13. pinkduck's avatar pinkduck says:
    1. It’s a definitional essay because even though it doesn’t define the disease itself, it still talks about what polio causes, does, and the effects it has on children.
    2. The clearest and briefest statement of this essay is about polio and smallpox and how they’ve been eliminated differently. While smallpox was eliminated with a specific formula, polio cannot be eradicated using that same formula.
    3. Polio is “sneakier, more resistant to both serums and human effort,” unlike smallpox. Meanwhile, smallpox is “obvious, defenseless, stable.”
  14. ChickenNugget's avatar ChickenNugget says:
    • This is a definition argument because even though it does not explicitly define polio, smallpox, or eradication, it clearly states the effects of these three terms, uses comparisons between the two diseases, and comparisons in the efforts to eradicate them. The essay explains who these three things effect and how it effects them. Because of this, the reader is able to easily identify what these terms mean.
    • I believe it is “…that the world could once again achieve with polio the triumph of man over disease that had been accomplished against smallpox. But similar efforts achieve similar results only when conditions are similar, and smallpox and polio are too different for the same formulas to work.”
    • Polio is not as easy to spot, polio vaccines need to be administered several times while smallpox only needs to be administered once, and polio vaccines themselves can infect patients with polio.
  15. pineapple488's avatar pineapple488 says:
    1. This is a definition essay because it defines Polio by comparing it to Smallpox as well as defining what Polio is NOT. By making these analogies, the reader gets an understanding of what Polio actually is in terms of its characteristics.
    2. The clearest and briefest statement of the thesis of this argument is “But similar efforts achieve similar results only when conditions are similar, and smallpox and polio are too different for the same formulas to work.”
    3. The difference between Smallpox and Polio that make it difficult for Polio to be eradicated is that Smallpox is more apparent and visible than Polio. Polio can be passed to hundreds of people before one even knows that they have it.
  16. GamersPet's avatar GamersPet says:

    How is this a Definition Essay? It doesn’t define polio, smallpox, or eradication?

    This essay describes the similarity and the difference of what a disease is. This whole essay talks about the concept of what a disease does to people, and it is affecting them physically.

    What is the clearest and briefest statement of the thesis of this argument?

    When it comes to forming a thesis statement in an argumentative essay is that it usually goes at the end of a paragraph that transitions to the next paragraph. I would believe its the very last sentence of the paragraph.

    “But similar efforts achieve similar results only when conditions are similar, and smallpox and polio are too different for the same formulas to work.”

    It’s like a proposal claim of stating that in order to get rid of polio is by doing the same methods with different formulas .

    What differences between polio and smallpox make it less likely that polio can be eradicated?

    The biggest difference that I read is that smallpox are easier to spot while polio does not. Polio accumulates overtime until it is too late to react to it. The key words that describes polio is silent but not deadly. Not only that but even if there is a vaccine for polio, there is a chance that the vaccine can do more harm to the host then what a it should have done.

  17. unicorn45678's avatar unicorn45678 says:
    1. This is a definition essay, even though it doesn’t define what smallpox, polio, or eradication is, it still mentions how these different types of diseases effects children’s well-being.
    2. The clearest and briefest statement of this thesis is smallpox and polio are two different diseases, and they can’t be treated with the same medication, each of them have to be different. “But similar efforts achieve similar results only when conditions are similar, and smallpox and polio are too different for the same formulas to work.”
    3. The differences between smallpox and polio are that smallpox is more visible than polio
  18. taco491's avatar taco491 says:

    1.How is this a Definition Essay? It doesn’t define polio, smallpox, or eradication.

          This is a definition essay because it describes similarities and differences between two diseases, which leads to the reader gather facts and learn more about them. Although it doesn’t specifically define polio, smallpox, or eradication, it describes it by comparing each of the diseases.

          2. What is the clearest and briefest statement of the thesis of this argument?

            The clearest and briefest statement of the thesis in this argument is “smallpox and polio are too different for the same formulas to work.”

            3. What differences between polio and smallpox make it less likely that polio can be eradicated?

              The difference between polio and smallpox that makes it hard for polio to be eradicated is that smallpox is way easier to spot if someone has it, while polio takes long to affect people. Polio is hard to see if someone has it, which leads to the problem of even finding a person who has this disease to help “cure” them. Also one of the big things is that polio is not as deadly as smallpox. This leads to no new solutions because it is not an immediate threat. Even with some new vaccines, it is more dangerous to take it because it could give you polio instead of preventing it; there is not much care to make a vaccine to prevent/cure the disease.

            1. Elongated lobster's avatar Elongated lobster says:
              1. This is a definition essay because it outlines the effects and complications that come with trying to eradicate polio. In this sense, it is defining what the issues are when it comes to dealing with polio.
              2. The clearest and briefest statement of the thesis of this argument is that polio and smallpox are different diseases, and thus would require different approaches to eradicating the disease.
              3. Most of polio’s complications are asymptomatic, especially early on, while smallpox has physical boils of sorts that make it easier to detect and deal with.
            2. Bagel&Coffee's avatar Bagel&Coffee says:

              How is this a Definition Essay? It doesn’t define polio, smallpox, or eradication.

              My first grade teacher once told me the subject of a paragraph is usually the first or second sentence, with the rest of the sentences in the paragraph providing support. However is not uncommon to see a writer do the opposite of this and feature the subject in the last sentence. This is usually paired with a strategy were the writer wants to hook the reader (with the subject acting as a sort of punchline).

              This post features something similar however on a larger scale of of paragraphs instead of sentences. The paragraph that sets the subject for the other paragraphs is towards the bottom of the body of the post (13th paragraph I would qualify it as):

              Polio is not smallpox: obvious, defenseless, stable. It’s nefarious, invisible until it strikes, and mutable. The 1% of cases that persisted after 2005 began to mutate. The world had failed to wipe out the last of the last viruses. Some children had only mucosal immunity while the virus thrived in their intestines. The carriers looked healthy but passed the virus to others undetected, especially in the toughest places, the remote villages and refugee camps where sanitation was crude at best and healthcare nonexistent.

              And for simplicity just focus in on the first line here: “Polio is not smallpox”. That is, in a nutshell, how this post is definitional in nature. All the paragraphs above, are support of this notion of polio not being smallpox; not even remotely close to it. The above paragraphs demonstrate that the symptoms are different, the strategy involved is different, the cure is different, and the challenges involved are different.

              The last two paragraphs (14 and 15) are a sort of segway of the present into the future, with the last I would specifically label as a conclusion.

              What is the clearest and briefest statement of the thesis of this argument?

              “Polio is not smallpox.”

              What differences between polio and smallpox make it less likely that polio can be eradicated?

              The symptoms are different, the strategy involved is different, the cure is different, and the challenges involved are different.

              Small pox is obvious due to red bumps. Polio is less obvious, the host case spread it while the virus is still incubating.

              Small pox has a more guttural reaction with its deadliness. Polio is like bad but doesn’t grab the public the same way since it sucks, but is not as severe. Yea, I mean some people need an iron lung to stay alive.

              Curing smallpox is just a single vaccine away. Polio is multiple does over period of time.

              Both viruses have seen momentum (aka a level of enthusiasm or zeal) from the world’s many nations to collectively rid the world of said viruses, however while smallpox was eliminated, there is the implication that comes with asking how much longer till we rid the world of polio; an indicator of patience (see momentum) growing thinner.

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